肿瘤性发热是多种恶性肿瘤发生发展和治疗过程中最为常见的并发症之一，尤多见于原发性肝癌、肺癌、血液系统肿瘤等。田建辉提出“正虚伏毒”是恶性肿瘤的核心病机之一，正气不足，伏毒郁积少阳，正邪相争，郁而发热是肿瘤性发热的重要病机，可从“少阳郁热”论治，通过“以人为本”，“杂合以治”的辨证治疗方法，灵活运用经方，巧用柴胡剂治疗，往往能够有效缓解患者临床症状，提高生活质量。附验案一则。
Neoplastic fever is one of the most common complications in the development and treatment of various malignant tumors, especially in preinvasive liver cancer, lung cancer, and hematological tumors. “Zhengxufudu” is the core pathogenesis of malignant tumors. The disease belongs to the category of “intra-injury fever” in traditional Chinese medicine. Compared with Western medicine, the side effects are less and the curative effect is more durable. Through the “people-oriented” and “hybridization and treatment” syndrome differentiation treatment methods, according to the dif-ferent pathogenesis of patients, deftly using the classical prescription “chaihu” to treat severe tu-mor diseases can effectively alleviate the clinical symptoms and improve the quality of life. One proven case was presented.