%0 Journal Article
%T SDF-1/CXCR4/CXCR7共同参与脑卒中后神经功能的再生修复<br>SDF-1/CXCR4/CXCR7 Are Jointly Involved in the Regeneration and Repair of Nerve Function after Stroke
%A 范延平
%A 张洪亮
%A 曲明娟
%A 栗世方
%J Advances in Clinical Medicine
%P 1360-1366
%@ 2161-8720
%D 2020
%I Hans Publishing
%R 10.12677/ACM.2020.107205
%X <div style=\"text-align:justify;\">
	神经再生与血管新生是脑卒中后机体自我修复机制的重要表现形式，此过程依赖SDF-1的介导。SDF-1是一种具有趋化特性的细胞信号因子，广泛的存在于免疫和中枢神经系统中，可与其受体CXCR4、CXCR7构成两条不同的信号通路共同参与脑缺血后神经再生修复这一过程。在这篇综述中我们总结了关于SDF-1/CXCR4/CXCR7在脑卒中后神经功能恢复中的相关研究进展。<br />
Neurogenesis and angiogenesis are important manifestations of the body’s self-repair mechanism after stroke, which is mediated by SDF-1. SDF-1 is a chemokine cell signaling factor, widely existing in the immune system and central nervous system. It can form two different signaling pathways with its receptors CXCR4 and CXCR7 to participate in the process of nerve regeneration and repair after cerebral ischemia. In this review, we summarized the progress of studies on SDF-1/ CXCR4/CXCR7 in neurological function recovery after stroke.
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%K 基质细胞衍生因子-1，CXCR4，CXCR7，脑卒中<br>SDF-1
%K CXCR4
%K CXCR7
%K Stroke
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=36602