%0 Journal Article %T Risk Factors Contributing in Increased Susceptibility and Severity of COVID-19 Infection during Pregnancy %A Imad R. Musa %J Open Journal of Obstetrics and Gynecology %P 1197-1215 %@ 2160-8806 %D 2020 %I Scientific Research Publishing %R 10.4236/ojog.2020.1090113 %X The corona virus disease 2019 (COVID-19) pandemic has spread globally and pregnant women are considerably prone to COVID-19 infection with increased maternal and perinatal complications. Aim: This study aims to explore the risk factors that contribute to susceptibility and severity of COVID-19 infection among pregnant women. Method: A literature search of articles relating to COVID-19 infection during pregnancy, was conducted, using PubMed, Scopus and Google scholar engine. Result: A total of 168 articles were initially identified. Eighty four papers were excluded for failing to address the aim of the study. After screening titles and abstracts, eighty four full-text articles were retrieved for eligibility analysis. Nineteen studies addressed the susceptibility related to pregnancy, twenty-two studies evaluated the associated comorbidities, nineteen focused on immune system, thirty-six articles concentrated on the risk of coagulopathy and eleven addressed more than one risk factor. Conclusion: Pregnancy, associated comorbidities, modulated immune response during pregnancy and risk of coagulopathy are considerable risk factors contributing to COVID-19 pathogenesis among pregnant women and may predict the outcome. %K Pregnancy %K Corona Virus %K COVID-19 %K SARS-CoV-2 %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=102888