%0 Journal Article %T Ankle每foot orthosis alignment affects running mechanics in individuals with lower limb injuries %A E Russell Esposito %A Jason M Wilken %A Kelly A Schmidtbauer %J Prosthetics and Orthotics International %@ 1746-1553 %D 2019 %R 10.1177/0309364619826386 %X Individuals with severe lower extremity injuries often require ankle每foot orthoses to return to normal activities. Ankle每foot orthoses alignment is a key consideration during the clinical fitting process and may be particularly important during dynamic activities such as running. To investigate how 3∼ changes in sagittal plane ankle每foot orthoses alignment affect running mechanics. Controlled laboratory study. Twelve participants with unilateral lower limb injury ran overground and lower extremity running mechanics were assessed. Participants wore their passive-dynamic ankle每foot orthoses in three alignments: clinically fit neutral, 3∼ plantarflexed from clinically fit neutral, and 3∼ dorsiflexed from clinically fit neutral. The 3∼ changes in sagittal alignment significantly influenced ankle mechanics during running. The plantarflexed alignment significantly decreased the peak ankle plantarflexor moment, peak knee extensor moment, and peak ankle and knee power absorption and generation compared to more dorsiflexed alignments. Alignment also altered footstrike angle, with dorsiflexed alignments associated with a more dorsiflexed footstrike pattern and plantarflexed alignments toward a more plantarflexed footstrike pattern. However, alignment did not influence loading rate. Small changes in ankle每foot orthoses alignment significantly altered running mechanics, including footstrike angle, and knee extensor moments. Understanding how ankle每foot orthoses design parameters affect running mechanics may aid the development of evidence-based prescription guidelines and improve function for ankle每foot orthoses users who perform high-impact activities. Understanding how ankle每foot orthoses alignment impacts biomechanics should be a consideration when fitting passive-dynamic devices for higher impact activities, such as running. Individual running styles, including footstrike patterns, may be affected by small changes in alignment %K Intrepid dynamic exoskeletal orthosis %K military %K footstrike %K limb salvage %K ankle每foot orthoses %K loading rate %U https://journals.sagepub.com/doi/full/10.1177/0309364619826386