%0 Journal Article
%T Efficacy of Cognitive Rehabilitation in Alzheimer Disease: A 1
%A Anne Quittre
%A Catherine Olivier
%A Eric Salmon
%A Fran£¿oise Lekeu
%A Sophie Germain
%A Vinciane Godichard
%A Vinciane Wojtasik
%J Journal of Geriatric Psychiatry and Neurology
%@ 1552-5708
%D 2019
%R 10.1177/0891988718813724
%X The benefit of cognitive rehabilitation (CR) for patients with early-stage Alzheimer disease (AD) remains difficult to assess. An observational, prospective study was conducted in a sample of 52 patients with AD included in a clinical, individualized CR program. Cognitive rehabilitation consisted of 1 weekly session during 3 months at home, followed by 1 monthly contact for 9 months. Rehabilitation techniques were used by experienced therapists to adapt activities important for the patient. Evaluation of patient¡¯s dependence in activities and objective and subjective caregiver¡¯s burden was performed with a research quantitative scale immediately after the intervention and at 6-month and 1-year follow-up. Analyses with repeated measure analysis of variance showed decreased patient¡¯s dependence for adapted activities at 3 months, 6 months, and 1 year. Objective and subjective percentage of caregiver¡¯s burden was also decreased at all evaluations with our research functional scale, while there was no change on Zarit¡¯s burden scale. Global cognition slightly decreased over 1 year. This observational study in a clinical setting is in line with the benefit of CR for patients with mild AD reported in recent randomized controlled trials. The benefit obtained for adapted activities remained after 1 year, even if global cognition declined. Moreover caregiver¡¯s burden related to all individually relevant daily activities (from a list of 98) evaluated within the CR program was decreased after 1 year. Those preliminary results emphasize the importance of choice for the measurement instrument to report CR efficacy and claim for further validation of such tools
%K cognitive rehabilitation
%K memory clinic
%K Alzheimer
%K daily activities
%K burden
%U https://journals.sagepub.com/doi/full/10.1177/0891988718813724