%0 Journal Article
%T Analysis of Two Quantitative Ultrasound Approaches
%A Aiguo Han
%A John W. Erdman
%A Michael P. Andre
%A Pauline Muleki-Seya
%A William D. O¡¯Brien
%J Ultrasonic Imaging
%@ 1096-0910
%D 2018
%R 10.1177/0161734617729159
%X There are two well-known ultrasonic approaches to extract sets of quantitative parameters: Lizzi¨CFeleppa (LF) parameters: slope, intercept, and midband; and quantitative ultrasound (QUS)¨Cderived parameters: effective scatterer diameter (ESD) and effective acoustic concentration (EAC). In this study, the relation between the LF and QUS-derived parameters is studied theoretically and experimentally on ex vivo mouse livers. As expected from the theory, LF slope is correlated to ESD ( R 2 = 1 . 00 ), and from experimental data, LF midband is correlated to EAC ( R 2 = 0 . 76 ). However, LF intercept is not correlated to ESD ( R 2 = 0 . 25 ) nor EAC ( R 2 = 0 . 07 ). The unexpected correlation observed between LF slope and EAC ( R 2 = 0 . 94 ) results likely from the high correlation between ESD and EAC due to the inversion process. For a liver fat percentage estimation, an important potential medical application, the parameters presenting the better correlation are EAC ( R 2 = 0 . 78 ) and LF midband ( R 2 = 0 . 70 )
%K quantitative ultrasound technique
%K QUS parameters
%K Lizzi¨CFeleppa parameters
%K mouse livers
%U https://journals.sagepub.com/doi/full/10.1177/0161734617729159