%0 Journal Article
%T Prediction of venous malformations with localized intravascular coagulopathy with diffusion
%A Ahmed AKA Razek
%A Germeen A Ashmalla
%J Phlebology
%@ 1758-1125
%D 2019
%R 10.1177/0268355518773528
%X Venous malformations may be complicated by localized intravascular coagulopathy which is a serious condition with hematological sequel. Prediction of localized intravascular coagulopathy is mandatory for prompt anticoagulation therapy. Laboratory and routine magnetic resonance imaging can predict localized intravascular coagulopathy in venous malformations; however, the results are variable. To predict venous malformations with localized intravascular coagulopathy with diffusion-weighted magnetic resonance imaging. A retrospective analysis was performed on 55 patients (34 male, 21 female aged 14¨C64 years: mean 39 years) with venous malformations that underwent diffusion-weighted magnetic resonance imaging. The apparent diffusion coefficient value of venous malformations was calculated. The mean apparent diffusion coefficient value of venous malformations with localized intravascular coagulopathy (n£¿=£¿26) (1.28£¿¡À£¿0.18£¿¡Á£¿10£¿3£¿mm2/s) was significantly different (P£¿=£¿0.001) from venous malformations without localized intravascular coagulopathy (n£¿=£¿29) (1.60£¿¡À£¿0.18£¿¡Á£¿10£¿3£¿mm2/s). When apparent diffusion coefficient value of 1.454£¿¡Á£¿10£¿3£¿mm2/s was used as a threshold value for the prediction of venous malformations with localized intravascular coagulopathy, the best result was obtained with an accuracy of 83.6%, sensitivity of 84.6%, specificity of 82.8%, and area under the curve of 0.895. The apparent diffusion coefficient value of venous malformations was correlated with D-dimer level (r£¿=£¿£¿0.59, P£¿=£¿0.006) and fibrinogen level (r£¿=£¿0.73, P£¿=£¿0.001). The apparent diffusion coefficient value is a non-invasive imaging parameter that can be used to predict venous malformations with localized intravascular coagulopathy
%K Diffusion
%K venous malformations
%K localized intravascular coagulopathy
%U https://journals.sagepub.com/doi/full/10.1177/0268355518773528