%0 Journal Article
%T Cardiovascular manifestations and patient outcomes following snake envenomation: a pilot study
%A Aditya John Binu
%A Ajay Kumar Mishra
%A Karthik Gunasekaran
%A Ramya Iyadurai
%J Tropical Doctor
%@ 1758-1133
%D 2019
%R 10.1177/0049475518814019
%X Cardiotoxicity in snake envenomation has not been adequately explored in the literature. This retrospective, observational study analysed clinical profiles and cardiovascular effects (CVE), with associated outcomes, in snake envenomation. Thirty-four patients were recruited between April 2014 and October 2017. Cardiovascular involvement was seen in 24 (70.6%) patients. Electrocardiographic changes included prolonged QTc (62.5%), T-wave inversion (37.5%) and tall T-waves (12.5%). Hospital stay was 7.2 (SD£¿=£¿5.3) days and 4.4 (SD£¿=£¿2.4) days in CVE and non-CVE groups respectively (P value£¿=£¿0.04). Mechanical ventilation was required only in nine of the CVE group (37.5%; P value£¿=£¿0.03). Shock was observed in seven patients (20.6%). Two of the patients in the CVE group (5.9%) died (P value£¿=£¿1.0); the majority had good outcomes with early administration of anti-venom serum and appropriate supportive measures. Thus, inpatient stay and mechanical ventilation were significantly increased in snake envenomation with CVEs, especially where an underlying co-morbidity existed
%K Asia
%K cardiovascular
%K physiology
%K diagnosis
%U https://journals.sagepub.com/doi/full/10.1177/0049475518814019