%0 Journal Article
%T Efficacy of a nurse
%A Consol Ivern
%A Cristina Enjuanes
%A Esther Marco
%A Jordi Bruguera
%A Josep Comin-Colet
%A Julio Marti-Almor
%A Merc¨¨ Cladellas
%A Miguel Cainzos-Achirica
%A Neus Badosa
%A Nuria Farre
%A Sonia Ruiz-Bustillo
%J European Journal of Cardiovascular Nursing
%@ 1873-1953
%D 2019
%R 10.1177/1474515119831511
%X Lack of achievement of secondary prevention objectives in patients with ischaemic heart disease remains an unmet need in this patient population. We aimed at evaluating the six-month efficacy of an intensive lipid-lowering intervention, coordinated by nurses and implemented after hospital discharge, in patients hospitalized for an ischaemic heart disease event. Randomized controlled trial, in which a nurse-led intervention including periodic follow-up, serial lipid level controls, and subsequent optimization of lipid-lowering therapy, if appropriate, was compared with standard of care alone in terms of serum lipid-level control at six months after discharge. The nurse-led intervention was associated with an improved management of low-density lipoprotein (LDL) cholesterol levels compared with standard of care alone: LDL cholesterol levels £¿100 mg/dL were achieved in 97% participants in the intervention arm as compared with 67% in the usual care arm (p value <0.001), the LDL cholesterol £¿70 mg/dL target recommended by the 2016 European Society of Cardiology guidelines was achieved in 62% vs. 37% participants (p value 0.047) and the LDL cholesterol reduction of £¿50% recommended by the American College of Cardiology/American Heart Association in 2013 was achieved in 25.6% of participants in the intervention arm as compared with 2.6% in the usual care arm (p value 0.007). The intervention was also associated with improved blood pressure control among individuals with hypertension. Our findings highlight the opportunity that nurse-led, intensive, post-discharge follow-up plans may represent for achieving LDL cholesterol guideline-recommended management objectives in patients with ischaemic heart disease. These findings should be replicated in larger cohorts
%K Nurse-led intervention
%K acute coronary syndrome
%K cholesterol
%K ischaemic heart disease
%K lipids
%K secondary prevention
%K statins
%U https://journals.sagepub.com/doi/full/10.1177/1474515119831511