%0 Journal Article
%T Comparison of the electrospray ionization (ESI) responses of penicillins with ESI responses of their methanolysis products
%A Lidia Podniesi¨½ska
%A Magdalena Fra¨½ska
%A Rafa£¿ Fra¨½ski
%J European Journal of Mass Spectrometry
%@ 1751-6838
%D 2019
%R 10.1177/1469066718820434
%X The electrospray ionization (ESI) responses, defined as the area of chromatographic peak of ion [M+H]+ obtained upon HPLC/ESI-MS analysis, of three ¦Â-lactam antibiotics, namely penicillin G, ampicillin and carbenicillin have been compared with the ESI responses of their methanolysis products. It has been found that methanolyzed penicillin G has much higher ESI response than the penicillin G. Methanolyzed ampicillin also has higher ESI response than ampicillin; however, the effect is less pronounced than for penicillin. Methanolyzed carbenicillin does not have pronouncedly higher ESI response than carbenicillin
%K ¦Â-Lactam antibiotic
%K penicillin G
%K ampicillin
%K carbenicillin
%K methanolysis
%K electrospray ionization
%K mass spectrometry
%K liquid chromatography
%U https://journals.sagepub.com/doi/full/10.1177/1469066718820434