%0 Journal Article
%T Factors affecting the concordance of radiologic and pathologic tumor size in breast carcinoma
%A Ahmed Alrajjal
%A Ameer Hamza
%A Daniel Ockner
%A Jacob Edens
%A Ramen Sakhi
%A Sajad Salehi
%A Shelby Miller
%A Sidrah Khawar
%A Warda Ibrar
%J Ultrasound
%@ 1743-1344
%D 2019
%R 10.1177/1742271X18804278
%X Radiologic assessment of tumor size is an integral part of the work-up for breast carcinoma. With improved radiologic equipment, surgical decision relies profoundly upon radiologic/clinical stage. We wanted to see the concordance between radiologic and pathologic tumor size to infer how accurate radiologic/clinical staging is. The surgical pathology and ultrasonography reports of patients with breast carcinoma were reviewed. Data were collected for 406 cases. Concordance was defined as a size difference within ¡À2£¿mm. The difference between radiologic and pathologic tumor size was within ¡À2£¿mm in 40.4% cases. The mean radiologic size was 1.73£¿¡À£¿1.06£¿cm. The mean pathologic size was 1.84£¿¡À£¿1.24£¿cm. A paired t-test showed a significant mean difference between radiologic and pathologic measurements (0.12£¿¡À£¿1.03£¿cm, p£¿=£¿0.03). Despite the size difference, stage classification was the same in 59.9% of cases. Radiologic size overestimated stage in 14.5% of cases and underestimated stage in 25.6% of cases. The concordance rate was significantly higher for tumors ¡Ü2£¿cm (pT1) (51.1%) as compared to those greater than 2£¿cm (¡ÝpT2) (19.7%) (p£¿<£¿0.0001). Significantly more lumpectomy specimens (47.5%) had concordance when compared to mastectomy specimens (29.8%) (p£¿<£¿0.0001). Invasive ductal carcinoma had better concordance compared to other tumors (p£¿=£¿0.02). Mean pathologic tumor size was significantly different from mean radiologic tumor size. Concordance was in just over 40% of cases and the stage classification was the same in about 60% of cases only. Therefore, surgical decision of lumpectomy versus mastectomy based on radiologic tumor size may not always be accurate
%K Breast carcinoma
%K tumor size
%K pathologic staging
%K breast ultrasound
%K concordance
%U https://journals.sagepub.com/doi/full/10.1177/1742271X18804278