%0 Journal Article
%T Evaluation of direct oral anticoagulants and vitamin K antagonists in mesenteric venous thrombosis
%A Anders Gotts£¿ter
%A Johan Elf
%A Moncef Zarrouk
%A Olle Ekberg
%A Saman Salim
%A Stefan Acosta
%J Phlebology
%@ 1758-1125
%D 2019
%R 10.1177/0268355518779517
%X Mesenteric venous thrombosis is a rare lethal disease. The main aim of the present study was to evaluate clinical efficacy and safety of direct oral anticoagulants and vitamin K antagonists in mesenteric venous thrombosis patients. Retrospective study of 102 mesenteric venous thrombosis patients treated between 2004 and 2017 at a center with a conservative medical first approach. Median clinical follow-up was 4 years. Computed tomography showed successful recanalization of thrombosis in 71% of patients on vitamin K antagonists and 69% of patients on direct oral anticoagulants (p£¿=£¿0.88). Overall major and esophageal variceal bleeding rate was 14.7% and 2.9%, respectively. No difference in major bleeding (p£¿=£¿0.54) was found between vitamin K antagonists and direct oral anticoagulants. No mesenteric venous thrombosis recurrence occurred during follow-up, and one venous thromboembolism occurred after cessation of anticoagulation. Anticoagulation with direct oral anticoagulants and vitamin K antagonists was efficient in patients with mesenteric venous thrombosis. Bleeding complications was a concern during treatment in both groups
%K Mesenteric venous thrombosis
%K direct oral anticoagulants
%K anticoagulation
%K efficacy
%K safety
%K recanalization
%K computed tomography
%U https://journals.sagepub.com/doi/full/10.1177/0268355518779517