%0 Journal Article
%T 41
%A Bruce L. Homer
%A Ken Dower
%J Toxicologic Pathology
%@ 1533-1601
%D 2018
%R 10.1177/0192623318803278
%X This symposium synopsis summarizes key results from a 41-week study of diabetic nephropathy (DN) in the type 2 diabetic ZSF1 fa/faCP rat model. During this study, we conducted longitudinal analysis of biomarkers, renal histopathology, ultrastructural assessment, renal quantitative image analysis, and transcriptome analysis of glomerular-enriched tissue. We concluded that there is translational value for using the ZSF1 rat model in mechanistic and therapeutic intervention efficacy studies for type 2 DN
%K diabetic nephropathy
%K ZSF1 rat model
%K diabetic kidney disease
%U https://journals.sagepub.com/doi/full/10.1177/0192623318803278