%0 Journal Article %T Clinical Problem %A Alexander R. Dietz %A Arun S. Varadhachary %A Asher J. Albertson %A John R. Younce %J The Neurohospitalist %@ 1941-8752 %D 2018 %R 10.1177/1941874418754966 %X Here we report the challenging case of a 41-year-old man with HIV complicated by AIDS and a history of prior neurologic injury from progressive multifocal leukoencephalopathy who presented with headache, fevers, lower extremity weakness, hyperreflexic upper extremities, and diminished lower extremity reflexes. We review the clinical decision-making and differential diagnosis for this presentation as the physical examination evolved and diagnostic testing changed over time %K spinal cord diseases %K HIV %K West Nile virus %U https://journals.sagepub.com/doi/full/10.1177/1941874418754966