%0 Journal Article %T Riociguat treatment for portopulmonary hypertension: a subgroup analysis from the PATENT %A Arno Fritsch %A Hossein-Ardeschir Ghofrani %A John Mattson %A Marc Humbert %A Michael Halank %A Michael Krowka %A Rodrigo Cartin-Ceba %J Pulmonary Circulation %@ 2045-8940 %D 2018 %R 10.1177/2045894018769305 %X In patients with portopulmonary hypertension (n£¿=£¿13) included in the 12-week randomized placebo-controlled PATENT-1 trial, riociguat was well tolerated and improved 6-min walking distance (6MWD), World Health Organization functional class (WHO FC), and other efficacy parameters; 6MWD and WHO FC improvements were sustained over two years in the open-label extension, PATENT-2 %K soluble guanylate cyclase stimulator %K portal hypertension %K pulmonary arterial hypertension %U https://journals.sagepub.com/doi/full/10.1177/2045894018769305