%0 Journal Article
%T The incremental shuttle walk test predicts mortality in non
%A A.A. Roger Thompson
%A Alexander M. Rothman
%A Allan Lawrie
%A Andrew J. Swift
%A Athanasios Charalampopoulos
%A Catherine G. Billings
%A Charlie A. Elliot
%A David G. Kiely
%A Iain J. Armstrong
%A Ian A. Smith
%A Ian Sabroe
%A Jim M. Wild
%A Judith A. Hurdman
%A Judith C. Waterhouse
%A Matthew Austin
%A Neil Hamilton
%A Robert Lewis
%A Robin Condliffe
%J Pulmonary Circulation
%@ 2045-8940
%D 2019
%R 10.1177/2045894019848649
%X Pulmonary hypertension (PH) is classified into five groups based on disease etiology but there is only limited information on the prognostic value of exercise testing in non-group 1 PH. In group 1 PH, the incremental shuttle walking test (ISWT) distance has been shown to correlate with pulmonary hemodynamics and predict survival without a ceiling effect. This study assessed the ISWT in non-group 1 PH. Data were retrieved from the ASPIRE Registry (Assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre) for consecutive patients diagnosed with PH. Patients were required to have been systematically assessed as group 2¨C5 PH and to have a baseline ISWT within three months of cardiac catheterization. Patients were stratified according to incremental shuttle walk test distance (ISWD) and ISWT distance percent predicted (ISWD%pred). A total of 479 patients with non-group 1 PH were identified. ISWD and ISWD%pred correlated significantly with symptoms and hemodynamic severity. ISWD and ISWD%pred predicted survival with no ceiling effect. The test was prognostic in groups 2, 3, and 4. ISWD and ISWD%pred and change in ISWD and ISWD%pred at one year were all significant predictors of outcome. In patients with non-group 1 PH the ISWT is a simple non-invasive test that is easy to perform, is predictive of survival at baseline and follow-up, reflects change, and can be used in the assessment of PH of any etiology
%K exercise testing
%K disease severity
%K prognosis
%U https://journals.sagepub.com/doi/full/10.1177/2045894019848649