%0 Journal Article %T Unsupervised PrEP in routine practice: a new challenge? %A Caroline Lions %A Catherine Tamalet %A H¨¦l¨¨ne Laroche %A Isabelle Poizot-Martin %A Olivia Zaegel-Faucher %J International Journal of STD & AIDS %@ 1758-1052 %D 2019 %R 10.1177/0956462419828872 %X Pre-exposure prophylaxis (PrEP) for the prevention of HIV infection with 300 mg daily tenofovir co-formulated with 200 mg emtricitabine is recommended as one prevention option for people who are at substantial risk of acquiring an HIV infection. We report the case of a 28-year-old man who has sex with men and who was referred to our unit for a primary HIV infection with positive p18, p24 and gp160 bands on Western blot analysis but with a low HIV plasma viral load. Although HIV misdiagnosis should always be considered in cases of atypical seroconversion pattern with a low viral burden, unsupervised PrEP should be systematically investigated %K Prevention %K human immunodeficiency virus %K sexual behaviour %K diagnosis %K treatment %U https://journals.sagepub.com/doi/full/10.1177/0956462419828872