%0 Journal Article %T An assisted structured reflection on life events and life goals in advanced cancer patients: Outcomes of a randomized controlled trial (Life InSight Application (LISA) study) %A Anneke M Westermann %A Annemieke Kuin %A Cecile Grootscholten %A Filip YFL De Vos %A Francesco Kortekaas %A Frans Bossink %A Hanneke WM Van Laarhoven %A Hantie P Kotz¨¦ %A Heinz-Josef Kl¨¹mpen %A Iris D Hartog %A Jacoba PM Van Der Loos %A Johannes BAM Schilderman %A Jolanda Schrama %A Martijn GH Van Oijen %A Michael Scherer-Rath %A Mirjam AG Sprangers %A Natascha AWP Schrama %A Renske Kruizinga %A Willem Blokland %A Willem Van De Vrande %A Wim G Meijer %J Palliative Medicine %@ 1477-030X %D 2019 %R 10.1177/0269216318816005 %X Diagnosis and treatment of incurable cancer as a life-changing experience evokes difficult existential questions. A structured reflection could improve patients¡¯ quality of life and spiritual well-being. We developed an interview model on life events and ultimate life goals and performed a randomized controlled trial to evaluate the effect thereof on quality of life and spiritual well-being. The intervention group had two consultations with a spiritual counselor. The control group received care as usual. EORTC QLQ-C15-PAL and the FACIT-sp were administered at baseline and 2 and 4£¿months after baseline. Linear mixed model analysis was performed to test between-group differences over time. Adult patients with incurable cancer and a life expectancy £¿6£¿months were randomized in a 1:1 ratio to the intervention or control group. A total of 153 patients from six different hospitals were included: 77 in the intervention group and 76 in the control group. Quality of life and spiritual well-being did not significantly change over time between groups. The experience of Meaning/Peace was found to significantly influence quality of life (¦Â£¿=£¿0.52, adj. R2£¿=£¿0.26) and satisfaction with life (¦Â£¿=£¿0.61, adj. R2£¿=£¿0.37). Although our newly developed interview model was well perceived by patients, we were not able to demonstrate a significant difference in quality of life and spiritual well-being between groups. Future interventions by spiritual counselors aimed at improving quality of life, and spiritual well-being should focus on the provision of sources of meaning and peace %K Oncology %K palliative care %K spirituality %K spiritual care %K spiritual care givers %K randomized controlled trials %U https://journals.sagepub.com/doi/full/10.1177/0269216318816005