%0 Journal Article
%T Sleep disordered breathing controlled by CPAP and sFlt
%A Amy Daly
%A Annemarie Hennessy
%A Annette Robertson
%A Colin Sullivan
%A Gabriele Bobek
%A Sally Middleton
%J Obstetric Medicine
%@ 1753-4968
%D 2018
%R 10.1177/1753495X17708949
%X There is recent interest exploring the possible impact of sleep disordered breathing on the mechanisms of preeclampsia. A biomarker of preeclampsia, soluble fms-like tyrosine kinase-1, has come to prominence in recent years. The aim of this study was to investigate the relationship between continuous positive airway pressure treatment, sleep disordered breathing and soluble fms-like tyrosine kinase-1 concentrations during pregnancy. A 38-year-old G1P0 presented at 20£¿+£¿5 weeks. She had a history of chronic hypertension. Sleep studies revealed she had sleep disordered breathing with an AHI of 7.3/h. She was commenced on continuous positive airway pressure. Soluble fms-like tyrosine kinase-1 concentrations and blood pressure recordings were taken at various points during her pregnancy. She did not develop preeclampsia or require an escalation in her antihypertensives. Soluble fms-like tyrosine kinase-1 concentrations rose 16% from a low baseline. She remained compliant with her continuous positive airway pressure. She progressed to birth a well, live, term baby. Continuous positive airway pressure treatment controlled sleep disordered breathing in a high risk pregnant woman with chronic hypertension with no increase in soluble fms-like tyrosine kinase-1 concentrations
%K Hypertension
%K sleep medicine
%U https://journals.sagepub.com/doi/full/10.1177/1753495X17708949