%0 Journal Article %T Multimodal analgesia for treatment of allodynia and hyperalgesia after major trauma in a cat %A Alejandra Bascu£¿¨¢n %A Alicia Vald¨¦s %A Mariela Goich %A Patricio Fa¨²ndez %J Journal of Feline Medicine and Surgery Open Reports %@ 2055-1169 %D 2019 %R 10.1177/2055116919855809 %X A 2-year-old polytraumatized male cat was admitted to a teaching hospital for correction of a defective inguinal herniorrhaphy. Upon arrival, the cat showed signs of neuropathic pain, including allodynia and hyperalgesia. Analgesic therapy was initiated with methadone and metamizole; however, 24 h later, the signs of pain continued. Reparative surgery was performed, and a multimodal analgesic regimen was administered (methadone, ketamine, wound catheter and epidural anesthesia). Postoperatively, the cat showed signs of severe pain, assessed using the UNESP-Botucatu multidimensional composite pain scale. Rescue analgesia was initiated, which included methadone, bupivacaine (subcutaneous wound-diffusion catheter) and transversus abdominis plane block. Because the response was incomplete, co-adjuvant therapy (pregabalin and electroacupuncture) was then implemented. Fourteen days after admission, the patient was discharged with oral tramadol and pregabalin for at-home treatment. Neuropathic pain is caused by a primary lesion or dysfunction in the nervous system and is a well-described complication following trauma, surgical procedures such as hernia repair, and inadequate analgesia. The aims of this report are to: (1) describe a presentation of neuropathic pain to highlight the recognition of clinical signs such as allodynia and hyperalgesia in cats; and (2) describe treatment of multi-origin, severe, long-standing, ¡®mixed¡¯ pain (acute inflammatory with a neuropathic component). The patient was managed using multiple analgesic strategies (multimodal analgesia), including opioids, non-steroidal anti-inflammatory drugs, locoregional anesthesia, co-adjuvant drugs and non-pharmacological therapy (electroacupuncture) %K Multimodal analgesia %K neuropathic pain %K allodynia %K hyperalgesia %K inguinal herniorrhaphy %K electroacupuncture %K pregabalin %U https://journals.sagepub.com/doi/full/10.1177/2055116919855809