%0 Journal Article
%T Preliminary evaluation of a predictive controller for a rotary blood pump based on pulmonary oxygen gas exchange
%A Feng Huang
%A Yang Fu
%A Zhe Gou
%J Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
%@ 2041-3033
%D 2019
%R 10.1177/0954411918823035
%X Physiological control of rotary blood pumps is becoming increasingly necessary for clinical use. In this study, the mean oxygen partial pressure in the upper airway was first quantitatively evaluated as a control objective for a rotary blood pump. A model-free predictive controller was designed based on this control objective. Then, the quantitative evaluation of the controller was implemented with a rotary blood pump model on a complete cardiovascular model incorporated with airway mechanics and gas exchange models. The results show that the controller maintained a mean oxygen partial pressure at a normal and constant level of 138£¿mmHg in the left heart failure condition and restored basic haemodynamics of blood circulation. A left ventricular contractility recovery condition was also replicated to assess the response of the controller, and a stable result was obtained. This study indicates the potential use of the oxygen partial pressure index during pulmonary gas exchange when developing a multi-objective physiological controller for rotary blood pumps
%K Physiological control
%K predictive control
%K rotary blood pump
%K pulmonary gas exchange
%K haemodynamics
%U https://journals.sagepub.com/doi/full/10.1177/0954411918823035