%0 Journal Article %T Effects of a multi %A Ali Bikmoradi %A Ali Reza Soltanian %A Mahnaz Khatiban %A Shiva Gomarverdi %J Journal of Infection Prevention %@ 1757-1782 %D 2019 %R 10.1177/1757177419830780 %X The standard precautions (SPs) should be disseminated and implemented by healthcare providers. This study aimed to examine the effects of a multi-component educational intervention on nurses¡¯ knowledge and adherence to the SP guidelines in intensive care units (ICUs). This small-scale study consisted of a cluster randomised trial. Two ICUs, located in different hospitals, participated in the study. Nurses (n = 15) in one ICU received the multi-component educational intervention. The intervention involved an educational (with multiple instructional media) and a behavioural (with hands-on practice) component. Nurses¡¯ knowledge and adherence were assessed at pre-test and two and six weeks after the intervention. Results showed significant group by time interaction effects for both outcomes: a large improvement was found in the experimental group over time, but not in the control group. The experimental nurses¡¯ knowledge improved from 15 ¡À 2.47 at pre-test to 19 ¡À 2.65 and 19.53 ¡À 0.92 at follow-ups. Similarly, their adherence increased from 19.87 ¡À 4.44 at pre-test to 29.20 ¡À 5.00 and 28.40 ¡À 4.37 at two and six weeks post-test, respectively. The multi-component educational interventions had demonstrated initial effectiveness in enhancing ICU nurses¡¯ knowledge and adherence to the SPs guidelines. The intervention is a promising approach for designing effective continuing education initiatives aimed to improve nurses¡¯ practice %K Education %K knowledge %K adherence %K standard precautions %K nurses %K intensive care unit %U https://journals.sagepub.com/doi/full/10.1177/1757177419830780