%0 Journal Article
%T High prevalence and indexes of anti
%A Adrian Wong
%A Alexander Lau
%A Allan Kermode
%A Angel Ng
%A Bonaventure Ip
%A Cheryl Au
%A Karen Ma
%A Lisa Au
%A Sze-Ho Ma
%A Vincent Mok
%A Wei Qiu
%J Multiple Sclerosis Journal
%@ 2055-2173
%D 2018
%R 10.1177/2055217318788699
%X We performed a cross-sectional study in 123 Chinese multiple sclerosis patients residing in Hong Kong to evaluate their anti-John Cunningham virus status using STRATIFY JCV DxSelect assays. Anti-John Cunningham virus antibody was present in 98/123 (80%) subjects, among which 75/98 (77%) had an anti-John Cunningham virus index ¡Ý1.5. Anti-John Cunningham virus antibody seropositivity was not correlated with age, disease duration, Expanded Disability Status Scale scores, types of multiple sclerosis (relapsing vs progressive), or disease-modifying treatments used. We found a very high seroprevalence and index of anti-John Cunningham virus antibodies in Chinese multiple sclerosis patients, which may impact the risk assessment and recommendation of disease-modifying treatments in this population
%K Anti-John Cunningham virus antibody
%K Chinese
%K anti-John Cunningham virus index
%K progressive multifocal leukoencephalopathy
%K multiple sclerosis
%U https://journals.sagepub.com/doi/full/10.1177/2055217318788699