%0 Journal Article %T Therapeutic strategy of central vein perforation accompanied by a mediastinal lesion after catheterization %A Chi-Chang Li %A Wei Zhang %A Xing-Jie Wu %A Yang Bu %A Zhi-Peng Zheng %J Journal of International Medical Research %@ 1473-2300 %D 2019 %R 10.1177/0300060519843686 %X Central vein perforation associated with a mediastinal lesion is a rare complication of catheterization. A 50-year-old woman was diagnosed with chronic kidney disease and required hemodialysis treatment. The patient developed central vein injury during attempted placement of a double-channel catheter. A computed tomographic scan and venography showed that the catheter had punctured the mediastinum from the central vein. After comprehensive assessment and multidisciplinary consultation, percutaneous catheter thrombin injection with follow-up balloon dilatation under fluoroscopy guidance successfully fixed the perforation. We summarize the therapeutic strategy of this complication and other treatment options, and discuss the related literature of central vein injury %K Catheterization %K central vein injury %K thrombin %K mediastinum %K hemodialysis %K kidney disease %K hemorrhage %U https://journals.sagepub.com/doi/full/10.1177/0300060519843686