%0 Journal Article
%T MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia
%A Genya Shimbo
%A Kazuro Miyahara
%A Masashi Yanagawa
%A Michihito Tagawa
%J Journal of Feline Medicine and Surgery Open Reports
%@ 2055-1169
%D 2018
%R 10.1177/2055116918801602
%X A 2-year-old neutered female domestic shorthair cat presented with a history of hypodipsia, recurrent hypernatraemia, pelvic limb ataxia and tremor. The serum arginine vasopressin level was low for the serum osmolality. MRI of the brain revealed a failure of separation of the cerebrum, which manifested as absence of the rostral part of the corpus callosum, fornix and septum pellucidum, thus resulting in a single fused ventricle. The diagnosis was lobar holoprosencephaly with hypodipsic hypernatraemia. To our knowledge, this is the first description of the MRI characteristics of lobar holoprosencephaly in a cat. This report suggests that MRI examination should be considered for precise diagnosis of hypodipsic hypernatraemia in young cats
%K Brain malformation
%K holoprosencephaly
%K hypernatraemia
%K hypodipsia
%K magnetic resonance imaging
%U https://journals.sagepub.com/doi/full/10.1177/2055116918801602