%0 Journal Article
%T Comparative familial aggregation of bipolar disorder in patients with bipolar I and bipolar II disorders
%A Gordon B Parker
%A Mia Romano
%A Rebecca K Graham
%A Tahlia Ricciardi
%J Australasian Psychiatry
%@ 1440-1665
%D 2018
%R 10.1177/1039856218772249
%X We sought to quantify the prevalence and differential prevalence of a bipolar disorder among family members of patients with a bipolar I or II disorder. The sample comprised 1165 bipolar and 1041 unipolar patients, with the former then sub-typed as having either a bipolar I or II condition. Family history data was obtained via an online self-report tool. Prevalence of a family member having a bipolar disorder (of either sub-type) was distinctive (36.8%). Patients with a bipolar I disorder reported a slightly higher family history (41.2%) compared to patients with a bipolar II disorder (36.3%), and with both significantly higher than the rate of bipolar disorder in family members of unipolar depressed patients (18.5%). Findings support the view that bipolar disorder is heritable. The comparable rates in the two bipolar sub-types support the positioning of bipolar II disorder as a valid condition with strong genetic underpinnings
%K bipolar disorder
%K heritability
%K family history
%U https://journals.sagepub.com/doi/full/10.1177/1039856218772249