%0 Journal Article
%T Bloodstream infections during post
%A Andrea Ballotta
%A Giuseppe Isgr¨°
%A Laurenzia Ferraris
%A Marco Ranucci
%A Mauro Cotza
%A Simona Silvetti
%A Valeria Pistuddi
%J The International Journal of Artificial Organs
%@ 1724-6040
%D 2019
%R 10.1177/0391398818817325
%X Veno-arterial extracorporeal membrane oxygenation after heart surgery is a relatively common procedure. It is easily applicable but associated with a number of complications, including bloodstream infections. The aim of this study is to determine the current rate and the risk factors related to bloodstream infections acquired during post-cardiotomy veno-arterial extracorporeal membrane oxygenation. Single-center retrospective study. From the overall population receiving any kind of extracorporeal membrane oxygenation from March 2013 through December 2017, the post-cardiotomy patient population was extracted, with a final sample of 92 veno-arterial extracorporeal membrane oxygenations. The risk of developing bloodstream infections as a function of extracorporeal membrane oxygenation exposure was analyzed with appropriate statistical analyses, including a Kaplan¨CMeier analysis. Overall, 14 (15.2%) patients developed a bloodstream infection during extracorporeal membrane oxygenation or within the first 48£¿h after extracorporeal membrane oxygenation removal. The total extracorporeal membrane oxygenation duration in the population was 567£¿days, and the incidence of bloodstream infections was 24.7 bloodstream infections/1000 extracorporeal membrane oxygenation days. There was a progressive increase in the cumulative hazard ratio during the first 7£¿days, reaching a value of 20% on day 7; from day 7 and day 15, the hazard ratio remained stable, with a second increase after day 15. The independent risk factors associated with bloodstream infections were adult age, pre-implantation serum total bilirubin level, and the amount of chest drain blood loss. Infections acquired during veno-arterial extracorporeal membrane oxygenation are common. Identify the risk factors that may improve strategies for treatment and prevention
%K Extracorporeal membrane oxygenation
%K infection
%K risk factors
%K cardiac surgery
%K bleeding
%U https://journals.sagepub.com/doi/full/10.1177/0391398818817325