%0 Journal Article
%T Quality of Life and Impact of Endoscopic Sinus Surgery in Adult Patients With Cystic Fibrosis
%A Cesare Braggion
%A Giandomenico Maggiore
%A Giovanni P. Santoro
%A Giuditta Mannelli
%A Maria S. Lazio
%A Oreste Gallo
%A Paolo Luparello
%A Silvia Bresci
%J American Journal of Rhinology & Allergy
%@ 1945-8932
%D 2019
%R 10.1177/1945892419839260
%X Cystic fibrosis (CF) is the most common autosomal recessive disease in Caucasian population. Due to its pathological mechanism, chronic rhino sinusitis (CRS) associated or not with nasal polyposis usually occurs in adults and affects close to one-half of all CF patients. The goal of our work was to evaluate the impact of endoscopic sinus surgery (ESS) in the quality of life (QoL) of the CF patients and demonstrate an improvement of the functional outcomes in the patients undergoing the surgical procedure rather than in the not treated ones. Methodology: We studied 54 adult patients affected by CF. Lund每Kennedy, Lund每Mackay scores, and Sino-Nasal Outcome Test-22 (SNOT-22) were analyzed. Twenty-two (40.7%) of the 54 CF patients underwent ESS. This group presented more likely complaints consistent with CRS. Lund每Kennedy and Lund每Mackay scores appeared higher in the ESS group: 10 (range of 6每12) and 16 (range of 12每20), respectively. SNOT-22 showed median values for non-ESS and ESS group of 17.5 (range of 3每68) and 44 (range of 10每73), respectively. ESS represents the best option to improve clinical QoL of CF patients who do not response to conventional medical therapy
%K cystic fibrosis
%K endoscopic sinus surgery
%K chronic rhino sinusitis
%K Sino-Nasal Outcome Test-22
%K quality of life
%U https://journals.sagepub.com/doi/full/10.1177/1945892419839260