%0 Journal Article
%T The effect of theta
%A Andreea Cotoi
%A Jerome Iruthayarajah
%A Magdalena Mirkowski
%A Rachel Anderson
%A Robert Teasell
%J Clinical Rehabilitation
%@ 1477-0873
%D 2019
%R 10.1177/0269215518804018
%X To evaluate the effectiveness of theta-burst stimulation for the treatment of stroke-induced unilateral spatial neglect. A systematic literature search was conducted from the inception of each database to 30 June 2018 using CINAHL, EMBASE, PubMed, PsycINFO, and Scopus. Articles were included if theta-burst stimulation was used to treat neglect following a stroke. The additional a priori inclusion criteria were as follows: (1) £¿3 adult (£¿18£¿years) participants, (2) £¿50% stroke population, and (3) peer-reviewed journal articles published in English. Extracted data included study and treatment characteristics, results, and adverse events. Nine studies met the inclusion criteria, generating a total of 148 participants. Eight studies evaluated a continuous stimulation protocol and one study investigated an intermittent stimulation protocol. Overall, both protocols significantly improved neglect severity when compared against placebo or active controls (P£¿<£¿0.05). Adding smooth pursuit training to theta-burst stimulation did not improve neglect relative to when the stimulation was delivered alone (P£¿>£¿0.05). There was inconsistent reporting of neglect terminology, outcome measures, and adverse events. The treatment characteristics were heterogeneous among the trials. This systematic review found that theta-burst stimulation seems to improve post-stroke unilateral spatial neglect, but because the evidence is limited to a few small studies with varied and inconsistent protocols and use of terminology, no firm conclusion on effectiveness can be drawn
%K Stroke
%K unilateral spatial neglect
%K neurorehabilitation
%K theta-burst stimulation
%K repetitive transcranial magnetic stimulation
%U https://journals.sagepub.com/doi/full/10.1177/0269215518804018