%0 Journal Article
%T Ankle
%A Ana Carolina Contente Braga de Souza
%A Ang¨¦lica Leite de Alcantara
%A Camila Cavalcante Koury
%A Danielle Dias da Silva
%A Fabr¨ªcio de Souza Resende
%A Franciane Trindade Cunha de Melo
%A Isabela Imbelloni Farias de Franco
%A Jo£¿o Fel¨ªcio Abrah£¿o Neto
%A Jo£¿o Soares Fel¨ªcio
%A Karem Mil¨¦o Fel¨ªcio
%A Luciana Marques da Costa Farias
%A Manuela Nascimento de Lemos
%A Maria Clara Neres Iunes de Oliveira
%A M¨¢rcia Costa dos Santos
%A Nathalie Abdallah Zahalan
%A Nat¨¦rcia Neves Marques de Queiroz
%A Norberto Jorge Kzan de Souza Neto
%A Rafael Jardim da Motta Corr¨ºa Pinto
%J Diabetes and Vascular Disease Research
%@ 1752-8984
%D 2019
%R 10.1177/1479164119829385
%X Peripheral arterial disease in patients with type 2 diabetes mellitus is an important risk factor for vascular events. Recommendations about whether ankle-brachial index should be performed differ depending on the source; therefore, it is necessary to re-evaluate the most important risk factors associated with peripheral arterial disease and whether it is useful to perform ankle-brachial index in newly diagnosed and drug-na£¿ve patients with diabetes, independent of age or peripheral arterial disease symptoms. A total of 711 subjects were divided into groups: group 1, 600 type 2 diabetes mellitus patients, symptomatic or not for peripheral arterial disease; group 2, 61 type 2 diabetes mellitus patients newly diagnosed and drug na£¿ve; and group 3, 50 subjects without diabetes. Ankle-brachial index, medical records and physical examination were performed in all patients, accessing cardiovascular risk factors. Analysing group 1 asymptomatic patient to peripheral arterial disease, we found abnormal ankle-brachial index in 49% (77/156) £¿50£¿years and 42% (16/38) <50£¿years (p£¿=£¿not significant). Considering drug-na£¿ve patients, a peripheral arterial disease prevalence of 39% (24/61) was found; among these, 48% (13/27) were <50£¿years and 32% (11/34) were £¿50£¿years (p£¿=£¿not significant). A forward stepwise regression model was developed, with type 2 diabetes mellitus duration (r2£¿=£¿0.12) and sedentary lifestyle (r2£¿=£¿0.14) found as independent variable predictors of severity of peripheral arterial disease, related to ankle-brachial index. We suggest that, in type 2 diabetes mellitus, ankle-brachial index should be measured at diagnosis. In addition, sedentary lifestyle was strongly associated with presence and severity of peripheral arterial disease
%K Peripheral arterial disease
%K diabetes mellitus
%K type 2 diabetes mellitus
%K ankle-brachial index
%U https://journals.sagepub.com/doi/full/10.1177/1479164119829385