%0 Journal Article
%T Open cystectomy is still alive and well: Outcomes from a single
%A Alexios Dosis
%A Blessing Dhliwayo
%A Iva Kovacevic
%A Jonathan Yee
%A Omer Ali
%A Patrick Jones
%A Pradip Javle
%A Rosie Blades
%J Journal of Clinical Urology
%@ 2051-4166
%D 2019
%R 10.1177/2051415818759366
%X To compare perioperative and oncological outcomes between open and laparoscopic radical cystectomy in a single-centre setting. This study was a retrospective cohort (level 2b evidence) non-randomised review of 228 radical cystectomies that were performed between January 2010 and February 2016. Primary outcome measures were operative time, complications, blood loss and length of hospital stay. Statistical analysis was performed using the SPSS v21.0. Quantitative values were compared with Student¡¯s t-test; categorical variables with the chi-square test. Statistical significance was considered a result of an alpha value less than 0.05. A Kaplan¨CMeier survival analysis was also conducted. Intraoperative blood loss was lower in laparoscopic surgery (855¡À673 vs. 716¡À570 mL, P=0.15), which had a significant impact on transfusion rates (P=0.02). Operative times were lower in open surgery (339¡À52.9 vs. 353.1¡À67.1 minutes, P=0.10), while hospital stay was lower in the laparoscopic group (14.2¡À11.2 vs. 16.0¡À13.6 days, P=0.28). Five-year survival rates were superior for patients who underwent an open procedure but were not statistically significant (P=0.10). This is, so far, the largest cohort to compare laparoscopic and open radical cystectomy. The laparoscopic approach can reduce the need for transfusion; however, there was no statistically significant difference in complication rates, duration of surgery, length of hospital stay or intraoperative blood loss, survival and margin positivity. Not applicable for this multicentre audit
%K Bladder cancer
%K laparoscopic
%K open
%K cystectomy
%K oncology
%U https://journals.sagepub.com/doi/full/10.1177/2051415818759366