%0 Journal Article
%T The Natural History of Labyrinthine Hemorrhage in Patients With Sudden Sensorineural Hearing Loss
%A Chang Lin
%A Chao-Jun Zeng
%A Jin-Mei Cheng
%A Rong Zhang
%A Xi-Hang Chen
%A Zhe-Ming Fang
%J Ear, Nose & Throat Journal
%@ 1942-7522
%D 2019
%R 10.1177/0145561319834862
%X To investigate the application of inner ear 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging (MRI) in patients with sudden sensorineural hearing loss (SSNHL) accompanied by inner ear hemorrhage. A total of 1252 SSNHL patients who were admitted from January 2010 to April 2018 were included in the study. The patients¡¯ clinical features, complete blood counts, coagulation profiles, audiometry data, and MRI scans were retrospectively reviewed. Twenty-four patients had high labyrinth signals on inner ear 3D-FLAIR MRI (24/1252, 1.9%) that were diagnosed as inner ear hemorrhage. One patient had endolymphatic hydrops on the contralesional side. In the 24 patients, pure tone audiometry curves revealed profound deafness (19/24) and flat moderate hearing loss (5/24); most patients had associated vertigo (23/24) and tinnitus (19/24). Patients with SSNHL (N = 24) were treated. Sixteen patients had invalid improvement, 3 patients were markedly improved, 4 patients had effective treatment, and only 1 patient was cured, for a therapeutic efficacy of 33.3% (8/24). Follow-up 3D-FLAIR MRI in patients showed absorbance of labyrinthine hemorrhage and disappearance of the high signal intensity in the inner ear within 2 weeks to 4 months. Inner ear 3D-FLAIR MRI indicate that most cases of inner ear hemorrhage are spontaneous and that high labyrinth signals are absorbed within 4 months. The site of labyrinth hemorrhage is irregular and independent of hearing loss. Conventional treatment is not very effective, and an appropriate therapy for SSNHL requires further investigation
%K Inner ear
%K labyrinthine hemorrhage
%K sudden sensorineural hearing loss
%K 3D-FLAIR
%K magnetic resonance imaging
%U https://journals.sagepub.com/doi/full/10.1177/0145561319834862