%0 Journal Article
%T Assessment of Efficacy of Oral Rehydration Salts in Children With Neurally Mediated Syncope of Different Hemodynamic Patterns
%A Cheng Wang
%A Chuanmei Tan
%A Runmei Zou
%A Shuo Wang
%A Wen Li
%A Xiaoyan Liu
%J Journal of Child Neurology
%@ 1708-8283
%D 2019
%R 10.1177/0883073818803035
%X To assess the efficacy of oral rehydration salts in children with neurally mediated syncope of different hemodynamic types. Children with unexplained syncope or pre-syncope who visited or were hospitalized between March 2012 and February 2015 were enrolled in the study. Checked by the head-up tilt test, 105 children (aged 4-18 years, with a mean age of 11.96 ¡À 2.86 years) were diagnosed with neurally mediated syncope. Of them, 73 had vasovagal syncope (vasodepressor type in 46, mixed/cardioinhibitory types in 27), and 32 had postural orthostatic tachycardia syndrome. They were randomized into the oral rehydration salts plus health education group (n = 55) and the health education alone group (n = 50). All treated children were followed up. The follow-up time ranged from 6 to 25 (14.82 ¡À 6.13) months. Short-term effects were assessed according to the recurrence of clinical symptoms and reviews of head-up tilt test results 6 months after drug withdrawal. Long-term effects were compared between both groups of children with neurally mediated syncope. Short-term effect: No significant differences were found in subjective response rate and head-up tilt test negative results rate among different hemodynamic types (P > .05). Long-term effect: Compared with the health education alone group, the cumulative response rate increased after treatment with oral rehydration salts (P < .05). Among oral rehydration salts¨Ctreated children, the cumulative response rate was higher in those with vasodepressor vasovagal syncope than with mixed/cardioinhibitory vasovagal syncope (P < .05). Compared with children with mixed/cardioinhibitory vasovagal syncope, oral rehydration salt is more suitable for those with vasodepressor vasovagal syncope
%K oral rehydration salts
%K hemodynamics
%K neurally mediated syncope
%K children
%U https://journals.sagepub.com/doi/full/10.1177/0883073818803035