%0 Journal Article
%T Health
%A Farkhondeh Sharif
%A Kate Khair
%A Masoume Rambod
%A Sylvia von Mackensen
%A Zahra Molazem
%J Clinical and Applied Thrombosis/Hemostasis
%@ 1938-2723
%D 2018
%R 10.1177/1076029618758954
%X Hemophilia causes bleeding that may affect patients¡¯ psychological aspects and quality of life. This study aims to evaluate the impact of psychological aspects and pain on health-related quality of life (HRQoL) in adult patients with hemophilia. This cross-sectional study was conducted on 103 patients with hemophilia. Data were collected using hemophilia-specific quality of life, Depression Anxiety Stress Scales, and pain visual analogue scales. Data were analyzed using correlation coefficients, analysis of covariance, and regression analysis. The results showed that 71.7% of patients with hemophilia experienced pain on the study day. The mean score of HRQoL of patients with hemophilia was 51.09 (standard deviation = 19.37). Moreover, 57.4%, 64.6%, and 44.6% of the patients had mild to severe depression, anxiety, and stress, respectively. In addition, a significant association was observed between HRQoL and depression, anxiety, and severity of pain. In the regression model, 48% of changes in HRQOL were explained by the study variables, with the severity of pain and depression being significant predictors. Therefore, attention should be paid to these aspects to improve patients¡¯ quality of life and psychosocial health
%K hemophilia
%K health-related quality of life
%K stress
%K anxiety
%K depression
%K Haem-A-QoL
%K DASS
%K pain
%U https://journals.sagepub.com/doi/full/10.1177/1076029618758954