%0 Journal Article
%T Cost
%A Breiffni Leavy
%A Conran Joseph
%A Erika Franz¨¦n
%A Maria Hagstr£¿mer
%A Niklas L£¿fgren
%A Nina Brodin
%J Clinical Rehabilitation
%@ 1477-0873
%D 2019
%R 10.1177/0269215518800832
%X To determine the cost-effectiveness of the HiBalance training program for managing Parkinson¡¯s disease (PD)-related balance and gait disorders. Cost comparison design following the randomized controlled trial comparing a novel balance training intervention with care as usual. A total of 100 participants with mild¨Cmoderate PD were randomized to either the intervention (n£¿=£¿51) or the control group (n£¿=£¿49). A 10-week (three times per week), group-based, progressive balance training program, led by two physical therapists. All program costs were collected for both groups. Cost-utility was evaluated using quality-adjusted life years (QALYs) and cost-effectiveness measures were the Mini Balance Evaluation Systems Test (Mini-BESTest; assessing balance performance) and gait velocity. Incremental cost-effectiveness ratios were calculated and a probabilistic sensitivity analysis was conducted. The between-group difference in QALYs was 0.043 (95% confidence interval (CI): 0.011¨C0.075), favoring the intervention group. Between-group differences in balance performance and gait velocity were 2.16 points (95% CI: 1.19¨C3.13) and 8.2£¿cm/second (95% CI: 2.9¨C13.6), respectively, favoring the intervention group. The mean cost per participant in the intervention group was 16,222£¿SEK (?1649) compared to 2696£¿SEK (?274) for controls. The estimated incremental cost-effectiveness ratios were 314,558£¿SEK (?31,969) for an additional QALY, 6262£¿SEK (?631) for one point improvement in balance performance, and 1650£¿SEK (?166) for 1£¿cm/second increase in gait velocity. Sensitivity analyses indicated a high probability (85%) of program success. In terms of QALYs, the HiBalance program demonstrated a high probability of cost-effectiveness in the short-term perspective when considering the willingness-to-pay thresholds used in Europe
%K Parkinson¡¯s disease
%K HiBalance training
%K cost-effectiveness
%K economic evaluation
%K quality-adjusted life years
%U https://journals.sagepub.com/doi/full/10.1177/0269215518800832