%0 Journal Article
%T Quality of Life in Patients Undergoing Spine Surgery: Systematic Review and Meta
%A Adetokunbo A. Obayemi
%A James H. Stephen
%A Matthew A. Piazza
%A Neil R. Malhotra
%A Nikhil R. Nayak
%A Sherman C. Stein
%J Global Spine Journal
%@ 2192-5690
%D 2019
%R 10.1177/2192568217701104
%X Meta-analysis. Despite the increasing importance of tracking clinical outcomes using valid patient-reported outcome measures, most providers do not routinely obtain baseline preoperative health-related quality of life (HRQoL) data in patients undergoing spine surgery, precluding objective outcomes analysis in individual practices. We conducted a meta-analysis of pre- and postoperative HRQoL data obtained from the most commonly published instruments to use as reference values. We searched PubMed, EMBASE, and an institutional registry for studies reporting EQ-5D, SF-6D, and Short Form-36 Physical Component Summary scores in patients undergoing surgery for degenerative cervical and lumbar spinal conditions published between 2000 and 2014. Observational data was pooled meta-analytically using an inverse variance-weighted, random-effects model, and statistical comparisons were performed. Ninety-nine articles were included in the final analysis. Baseline HRQoL scores varied by diagnosis for each of the 3 instruments. On average, postoperative HRQoL scores significantly improved following surgical intervention for each diagnosis using each instrument. There were statistically significant differences in baseline utility values between the EQ-5D and SF-6D instruments for all lumbar diagnoses. The pooled HRQoL values presented in this study may be used by practitioners who would otherwise be precluded from quantifying their surgical outcomes due to a lack of baseline data. The results highlight differences in HRQoL between different degenerative spinal diagnoses, as well as the discrepancy between 2 common utility-based instruments. These findings emphasize the need to be cognizant of the specific instruments used when comparing the results of outcome studies
%K spine surgery
%K spine outcomes
%K quality-of-life
%K EQ-5Q
%K SF-6D
%U https://journals.sagepub.com/doi/full/10.1177/2192568217701104