%0 Journal Article %T The L %A Hans-Peter Ludin %J Clinical and Translational Neuroscience %@ 2514-183X %D 2018 %R 10.1177/2514183X18765401 %X Since almost 50 years L-Dopa is the gold standard for the treatment of patients with Parkinson¡¯s disease (PD). For the first time, a specific chemical abnormality was found in a specific brain disorder. It has been shown that the striatal dopamine (DA) content is greatly reduced in PD patients. The substitution of DA by its precursor L-dopa greatly enhanced the quality of life of PD patients %K Parkinson¡¯s disease %K dopamine %K L-dopa %K history %U https://journals.sagepub.com/doi/full/10.1177/2514183X18765401