%0 Journal Article %T Changes in Health %A Carsten Hendriksen %A Henning Langberg %A Jesper H. Pedersen %A Jette Vibe-Petersen %A Karen Trier %A Karl B. Christensen %A Klaus R. Larsen %A Maja S. Sommer %A Malene Missel %A Merete Christensen %A Paul F. Clementsen %A Seppo W. Langer %J Integrative Cancer Therapies %@ 1552-695X %D 2018 %R 10.1177/1534735416668258 %X Introduction: Surgical resection in patients with non¨Csmall cell lung cancer (NSCLC) may be associated with significant morbidity, functional limitations, and decreased quality of life. Objectives: The objective is to present health-related quality of life (HRQoL) changes over time before and 1 year after surgery in patients with NSCLC participating in a rehabilitation program. Methods: Forty patients with NSCLC in disease stage I to IIIa, referred for surgical resection at the Department of Cardiothoracic Surgery RT, Rigshospitalet, were included in the study. The rehabilitation program comprised supervised group exercise program, 2 hours weekly for 12 weeks, combined with individual counseling. The study endpoints were self-reported HRQoL (Functional Assessment of Cancer Therapy¨CLung, European Organization for Research and Treatment in Cancer¨CQuality of Life Questionnaire-QLQ-C30, Short-Form-36) and self-reported distress, anxiety, depression, and social support (National Comprehensive Cancer Network Distress Thermometer, Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support), measured presurgery, postintervention, 6 months, and 1 year after surgery. Results: Forty patients were included, 73% of whom completed rehabilitation. Results on emotional well-being (P < .0001), global quality of life (P = .0032), and mental health component score (P = .0004) showed an overall statistically significant improvement during the study. Conclusion: This feasibility study demonstrated that global quality of life, mental health, and emotional well-being improved significantly during the study, from time of diagnosis until 1 year after resection, in patients with NSCLC participating in rehabilitation %K lung cancer %K exercise %K rehabilitation %K NSCLC %K HRQoL %U https://journals.sagepub.com/doi/full/10.1177/1534735416668258