%0 Journal Article
%T Early life influences on child weight outcomes in the Study to Explore Early Development
%A Aleda Thompson
%A AnnJosette Ramirez
%A Carolyn G DiGuiseppi
%A Chyrise B Bradley
%A Gayle Windham
%A Jennifer A Pinto-Martin
%A Jesse Chittams
%A Juhi Pandey
%A Julie L Daniels
%A Laura A Schieve
%A Lisa Young
%A Neloufar Rahai
%A Susan E Levy
%A Susan L Johnson
%A Tanja VE Kral
%A Whitney York
%J Autism
%@ 1461-7005
%D 2019
%R 10.1177/1362361318791545
%X We examined associations between child body mass index at 2每5ˋyears and maternal pre-pregnancy body mass index, gestational weight gain, and rapid weight gain during infancy in children with autism spectrum disorder, developmental delays, or population controls. The Study to Explore Early Development is a multi-site case每control study of children, aged 2每5ˋyears, classified as autism spectrum disorder (nˋ=ˋ668), developmental delays (nˋ=ˋ914), or population controls (nˋ=ˋ884). Maternal gestational weight gain was compared to the Institute of Medicine recommendations. Rapid weight gain was a change in weight-for-age z-scores from birth to 6ˋmonthsˋ>ˋ0.67 standard deviations. After adjusting for case status, mothers with pre-pregnancy overweight/obesity were 2.38 times (95% confidence interval: 1.96每2.90) more likely, and mothers who exceeded gestational weight gain recommendations were 1.48 times (95% confidence interval: 1.17每1.87) more likely, to have an overweight/obese child than other mothers (Pˋ<ˋ0.001). Children with autism spectrum disorder showed the highest frequency of rapid weight gain (44%) and were 3.47 times (95% confidence interval: 1.85每6.51) more likely to be overweight/obese as children with autism spectrum disorder without rapid weight gain (Pˋ<ˋ0.001). Helping mothers achieve a healthy pre-pregnancy body mass index and gestational weight gain represent important targets for all children. Healthy infant growth patterns carry special importance for children at increased risk for an autism spectrum disorder diagnosis
%K autism spectrum disorder
%K gestational weight gain
%K maternal obesity
%K medical comorbidity
%K obesity
%U https://journals.sagepub.com/doi/full/10.1177/1362361318791545