%0 Journal Article
%T Burden of hospitalization in clinically diagnosed peripheral artery disease: A community
%A Adelaide M Arruda-Olson
%A Bradley R Lewis
%A Christopher G Scott
%A Homam Moussa Pacha
%A Hongfang Liu
%A Iftikhar J Kullo
%A Iyad Isseh
%A Kent Bailey
%A Naveed Afzal
%A Raad Haddad
%A Sara Abram
%A Thom W Rooke
%J Vascular Medicine
%@ 1477-0377
%D 2018
%R 10.1177/1358863X17736152
%X The burden and predictors of hospitalization over time in community-based patients with peripheral artery disease (PAD) have not been established. This study evaluates the frequency, reasons and predictors of hospitalization over time in community-based patients with PAD. We assembled an inception cohort of 1798 PAD cases from Olmsted County, MN, USA (mean age 71.2 years, 44% female) from 1 January 1998 through 31 December 2011 who were followed until 2014. Two age- and sex-matched controls (n = 3596) were identified for each case. ICD-9 codes were used to ascertain the primary reasons for hospitalization. Patients were censored at death or last follow-up. The most frequent reasons for hospitalization were non-cardiovascular: 68% of 8706 hospitalizations in cases and 78% of 8005 hospitalizations in controls. A total of 1533 (85%) cases and 2286 (64%) controls (p < 0.001) were hospitalized at least once; 1262 (70%) cases and 1588 (44%) controls (p < 0.001) ¡Ý two times. In adjusted models, age, prior hospitalization and comorbid conditions were independently associated with increased risk of recurrent hospitalizations in both groups. In cases, severe PAD (ankle¨Cbrachial index < 0.5) (HR: 1.25; 95% CI: 1.15, 1.36) and poorly compressible arteries (HR: 1.26; 95% CI: 1.16, 1.38) were each associated with increased risk for recurrent hospitalization. We demonstrate an increased rate of hospitalization in community-based patients with PAD and identify predictors of recurrent hospitalizations. These observations may inform strategies to reduce the burden of hospitalization of PAD patients
%K hospitalization
%K peripheral artery disease (PAD)
%K vascular medicine
%U https://journals.sagepub.com/doi/full/10.1177/1358863X17736152