%0 Journal Article
%T Postoperative complications and 90
%A Alchiede Simonato
%A Carlo Pavone
%A Dario Fontana
%A Luigi Candela
%J Urologia Journal
%@ 1724-6075
%D 2018
%R 10.1177/0391560317751600
%X Assessing the incidence of immediate postoperative complications and 90-day mortality in high-risk patients who have undergone radical cystectomy; evaluating the correlation between preoperative conditions and surgery outcomes. This is a monocentric retrospective observational study in which data of 65 patients have been analyzed. (a) Age ≡75ˋyears, (b) obesity, (c) age-adjusted Charlson Comorbidity Index ≡8, (d) anemic status, and (e) pT ≡3. More than 50% of patients had two or more ※high-risk§ indicators. Postoperative complications were assessed through Clavien每Dindo classification. Average age of patients was 70.4ˋyears, average age-adjusted Charlson Comorbidity Index was 5.8, and average body mass index was 27.5. In 28% of patients, no complications arose, while in 46% grades I每II complications according to Clavien每Dindo occurred, in 23% grades III每IV complications occurred, and in 3% of the patients, death arose in the immediate postoperative period (grade V). Overall, 90-day mortality rate after surgery was 12.3%. The age ≡75ˋyears and an age-adjusted Charlson Comorbidity Index score ≡8 have shown to be risk factors for the onset of severe complications (odds ratioˋ=ˋ3.54, pˋ=ˋ0.028 and odds ratioˋ=ˋ4.7, pˋ=ˋ0.026), while preoperative anemic status was a risk factor for complications in general (odds ratioˋ=ˋ4.1, pˋ=ˋ0.015). No analyzed parameter was a predictor of 90-day mortality (pˋ>ˋ0.05). Immediate postoperative complications and 90-day mortality in radical cystectomy in high-risk patients remain significant, but still in line with the data in the literature on comparable populations. Some of the preoperative parameters were able to predict the outcomes of the intervention with regard to the onset of complications but not to the 90-day mortality
%K Radical cystectomy
%K bladder cancer
%K Clavien每Dindo classification
%K complications and mortality
%U https://journals.sagepub.com/doi/full/10.1177/0391560317751600