%0 Journal Article
%T Fast assessment and management of chest pain patients without ST
%A Aize van der Sluis
%A Arend Mosterd
%A Arnoud WJ van ¡¯t Hof
%A Danish Ali
%A Erik Badings
%A Fred van Eenennaam
%A Jurri£¿n M ten Berg
%A Marion J Fokkert
%A Maycel Ishak
%A Robbert J Slingerland
%A Rudolf T Tolsma
%J European Heart Journal: Acute Cardiovascular Care
%@ 2048-8734
%D 2018
%R 10.1177/2048872616687116
%X The first study of the FamouS Triage project investigates the feasibility of ruling out a myocardial infarction in pre-hospital chest pain patients without electrocardiographic ST-segment elevation by using the modified HEART score at the patient¡¯s home, incorporating only a single highly sensitive troponin T measurement. A venous blood sample was drawn in the ambulance from 1127 consecutive chest pain patients for measurement of the pre-hospital highly sensitive troponin T levels, in order to establish a pre-hospital HEART score (i.e. the modified HEART score) and evaluate the possibility of triage at the patient¡¯s home. The primary endpoint was the occurrence of a major adverse cardiac event (MACE) i.e. acute myocardial infarction, percutaneous coronary intervention, coronary artery bypass grafting or death within 30 days after initial presentation. Two hundred and six patients (18%) developed a MACE during 30 days of follow-up. Thirty-six per cent of the patients (n=403) had a low modified HEART score (0¨C3 points) and none of them developed a MACE during follow-up. Forty-four per cent of the patients (n=494) had an intermediate modified HEART score (4¨C6 points) and 18% of them developed a MACE. Twenty per cent of the patients (n=230) had a high modified HEART score (7¨C10 points) of which 52% developed a MACE during follow-up. It seems feasible to rule out a myocardial infarction at home in chest pain patients without ST-segment elevation by using the modified HEART score. TRIAL ID: NTR4205. Dutch Trial Register [http://www.trialregister.nl]: trial number 4205
%K Pre-hospital triage
%K chest pain
%K non-ST-segment elevation acute coronary syndrome
%K acute myocardial infarction
%K modified HEART score
%K highly sensitive troponin
%U https://journals.sagepub.com/doi/full/10.1177/2048872616687116