%0 Journal Article
%T Total Synthesis of (8S) and (8R) Methyl 8
%A Akiko Yamada
%A Hideyuki Matsuura
%A Kosaku Takahashi
%A Rishni Masimbula
%J Natural Product Communications
%@ 1555-9475
%D 2019
%R 10.1177/1934578X19861013
%X The first total synthesis of (8R) and (8S) methyl ¦Â-d-glucopyranosyl helianthenate B was accomplished using the Cadiot-Chodkiewicz coupling reaction as a key step. Significant differences were observed in the resonances between the 1H-NMR and 13C-NMR spectra of the diastereomers. Based on these results, the absolute configurations of glucopyranosyloxymethine in methyl ¦Â-d-glucopyranosyl helianthenate A to E (1 -5) were reconfirmed to be the (R) configuration
%K Helianthenate
%K Cadiot-Chodkiewicz coupling
%K Jerusalem artichoke
%K Helianthus tuberosus
%U https://journals.sagepub.com/doi/full/10.1177/1934578X19861013