%0 Journal Article %T Falsely low activated clotting time measured in a patient with sickle cell trait %A Kyrie Wheeler %A Richard Crook %J Perfusion %@ 1477-111X %D 2019 %R 10.1177/0267659118822945 %X Sickle cell anaemia results from homozygosity of an A-T point mutation leading to a substitution of glutamic acid for valine at point 6 of the ¦Â-globin gene. A person with sickle cell trait inherits one normal and one mutated allele. Patients with sickle cell anaemia, and to a lesser extent sickle cell trait, have a wide spectrum of haemostatic abnormalities. Here we describe the problems faced in obtaining an accurate activated clotting time measurement, in a patient with sickle cell trait, prior to commencement of cardiopulmonary bypass for decannulation of Berlin Heart %K cardiopulmonary bypass %K sickle cell %U https://journals.sagepub.com/doi/full/10.1177/0267659118822945