%0 Journal Article
%T Perception of stigma in patients with primary progressive multiple sclerosis
%A Antonio Garc¨ªa-Merino
%A Bonaventura Casanova-Estruch
%A Daniel Prefasi
%A Francisco Gasc¨®n
%A Francisco P¨¦rez-Miralles
%A Guillermo Izquierdo
%A Jorge Maurino
%A Jos¨¦ R Ara
%A Lluis Rami¨®-Torrent¨¤
%A Lucienne Costa-Frossard
%A Mar¨ªa L Mart¨ªnez-Gin¨¦s
%A Sara Moreno-Garc¨ªa
%A Virginia Meca-Lallana
%A ¨®scar Fern¨¢ndez
%J Multiple Sclerosis Journal
%@ 2055-2173
%D 2019
%R 10.1177/2055217319852717
%X Stigma associated with neurological disorders may contribute to a poor health-related quality of life. However, limited information is available in primary progressive multiple sclerosis. We investigated the presence and impact of stigma in patients with primary progressive multiple sclerosis. A non-interventional, cross-sectional study was conducted. A total of 55 primary progressive multiple sclerosis patients were studied (mean age 55.8¡À9.5 years, 56.4% male). The median Expanded Disability Status Scale score was 5.5 (4.0¨C6.5). Stigma prevalence was 78.2% (n=43). Twenty-four patients (43.6%) were classified as depressed. Scores on the eight-item Stigma Scale for Chronic Illness correlated with physical (rho=0.464, p<0.001) and psychological (rho=0.358, p=0.007) 29-item Multiple Sclerosis Impact Scale subscores. Stigma predicted concurrent depression (odds ratio=1.13; p=0.046). Stigma was highly prevalent with a detrimental effect on quality of life and mood in primary progressive multiple sclerosis
%K Primary progressive multiple sclerosis
%K stigma
%K health-related quality of life
%K depression
%K patient-reported outcomes
%U https://journals.sagepub.com/doi/full/10.1177/2055217319852717