%0 Journal Article
%T Balloon Dilation of the Eustachian Tube: 12
%A Ameet Singh
%A C. Layton Elliott
%A Charles Syms
%A Christopher Hilton
%A Dennis Poe
%A John Leopold
%A John McElveen
%A John Sugrue
%A Joshua Light
%A Karen Hoffmann
%A Marc Dean
%A Mark Widick
%A Moises Arriaga
%A Nathan Nachlas
%A Neil Brown
%A Pablo Stolovitzky
%A Paul Guillory
%A Raymond Weiss
%A Seth Rosenberg
%A Vijay Anand
%A William Roberts
%J Otolaryngology¨CHead and Neck Surgery
%@ 1097-6817
%D 2019
%R 10.1177/0194599818821938
%X Obstructive eustachian tube dysfunction (OETD) affects up to 5% of adults; however, available treatment strategies have limitations. It was previously reported that balloon dilation of the eustachian tube (BDET) with the eustachian tube balloon catheter + medical management (MM) results in a significantly higher proportion of subjects with normalized tympanograms versus MM alone at 6- and 24-week follow-up. The current analysis extends these initial findings by investigating the durability of BDET + MM treatment outcomes through 52 weeks. Prospective cohort follow-up study from the treatment group in a previously reported multicenter randomized controlled trial. Twenty-one investigational sites across the United States. Here we report on secondary and exploratory endpoints for patients with OETD who previously failed MM and were randomized to the BDET + MM cohort. Analyses of tympanogram outcomes are reported by ear, unless specified otherwise, as a more accurate measure of durability of the procedure over time. Among subjects randomized to BDET + MM, the overall number with normalized tympanograms and ETDQ-7 scores (Eustachian Tube Dysfunction Questionnaire¨C7) remained comparable to those reported at 6- versus 52-week follow-up: tympanograms, 73 of 143 (51.0%) versus 71 of 128 (55.5%); ETDQ-7, 79 of 142 (55.6%) versus 71 of 124 (57.3%). The overall number of ears with normalized tympanograms also remained comparable, with 117 of 204 (57%) versus 119 of 187 (63.6%). The present study suggests that the beneficial effects of BDET + MM on tympanogram normalization and symptoms of subjects with refractory OETD demonstrate significant durability that is clinically relevant through 52 weeks
%K eustachian tube dysfunction
%K balloon catheter
%K normalization of tympanogram
%U https://journals.sagepub.com/doi/full/10.1177/0194599818821938