%0 Journal Article
%T Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
%A John J. Ryan
%A Meghan M. Cirulis
%A Stephen L. Archer
%J Pulmonary Circulation
%@ 2045-8940
%D 2019
%R 10.1177/2045894019834890
%X Arrhythmias are increasingly recognized as serious, end-stage complications of pre-capillary pulmonary hypertension, including pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Although arrhythmias contribute to symptoms, morbidity, in-hospital mortality, and possibly sudden death in PAH/CTEPH, there remains a paucity of epidemiologic, pathophysiologic, and outcome data to guide management of these patients. This review summarizes the most current evidence on the topic: from the molecular mechanisms driving arrhythmia in the hypertrophied or failing right heart, to the clinical aspects of epidemiology, diagnosis, and management
%K sudden death
%K prognosis
%K survival
%K atrial fibrillation
%K supraventricular atrial arrhythmia
%K atrial flutter
%K right heart failure
%U https://journals.sagepub.com/doi/full/10.1177/2045894019834890