%0 Journal Article
%T Barriers and enablers to deprescribing in people with a life
%A Koen Pardon
%A Kristel Paque
%A Luc Deliens
%A Monique Elseviers
%A Robert Vander Stichele
%A Thierry Christiaens
%A Tinne Dilles
%J Palliative Medicine
%@ 1477-030X
%D 2019
%R 10.1177/0269216318801124
%X Knowing the barriers/enablers to deprescribing in people with a life-limiting disease is crucial for the development of successful deprescribing interventions. These barriers/enablers have been studied, but the available evidence has not been summarized in a systematic review. To identify the barriers/enablers to deprescribing of medications in people with a life-limiting disease. Systematic review, registered in PROSPERO (CRD42017073693). A systematic search of MEDLINE, Embase, Web of Science and CENTRAL was conducted and extended with a hand search. Peer-reviewed, primary studies reporting on barriers/enablers to deprescribing in the context of explicit life-limiting disease were included in this review. A total of 1026 references were checked. Five studies met the criteria and were included in this review. Three types of barriers/enablers were found: organizational, professional and patient (family)-related barriers/enablers. The most prominent enablers were organizational support (e.g. for standardized medication review), involvement of multidisciplinary teams in medication review and the perception of the importance of coming to a joint decision regarding deprescribing, which highlighted the need for interdisciplinary collaboration and involving the patient and his family in the decision-making process. The most important barriers were shortages in staff and the perceived difficulty or resistance of the nursing home resident¡¯s family ¨C or the resident himself. The scarcity of findings in the literature highlights the importance of filling this gap. Further research should focus on deepening the knowledge on these barriers/enablers in order to develop sustainable multifaceted deprescribing interventions in palliative care
%K Drug utilization
%K deprescriptions
%K palliative care
%K systematic review
%U https://journals.sagepub.com/doi/full/10.1177/0269216318801124