%0 Journal Article
%T Discordance of Twin Placentas for Multifocal Eosinophilic/T
%A Erik W Nohr
%A James R Wright
%J Pediatric and Developmental Pathology
%@ 1615-5742
%D 2019
%R 10.1177/1093526618783256
%X Eosinophilic/T-cell chorionic vasculitis (ETCV) is an idiopathic placental lesion characterized by chorionic vasculitis composed predominantly of eosinophils and CD3+ T lymphocytes. It usually presents as a unifocal lesion, but a subset have multifocal involvement. We report 4 Di-Di and 2 Di-Mo twins sharing fused placental discs with discordant circulatory involvement by multifocal ETCV. The findings are difficult to explain by sampling alone. The limitation of ETCV to 1 fetus¡¯s vascular territory in monozygotic twin pregnancies is difficult to explain but could provide insights into the fetal immune system and the etiology of ETCV
%K eosinophilic/T-cell chorionic vasculitis
%K inflammation
%K monochorionic
%K multifocal
%K placenta
%K twin pregnancy
%U https://journals.sagepub.com/doi/full/10.1177/1093526618783256