%0 Journal Article
%T Clinical considerations of hyaluronidase as an adjunct to subcutaneous rituximab injection
%A Anne Dar Santos
%A M¨¢rio L de Lemos
%J Journal of Oncology Pharmacy Practice
%@ 1477-092X
%D 2019
%R 10.1177/1078155218817819
%X Subcutaneous rituximab injectables are formulated with recombinant human hyaluronidase as an adjunct to facilitate the absorption of the large volume of rituximab. We review the clinical considerations regarding the potential for systemic hyaluronidase toxicity and increased systemic absorption of subcutaneous or topical drugs administered subsequent to rituximab
%K Hyaluronidase
%K rituximab
%K subcutaneous injection
%K dermis
%K antineoplastic agent
%U https://journals.sagepub.com/doi/full/10.1177/1078155218817819